10-Year Data Shows Accuray CyberKnife® System Provides Long-Lasting Relief of the Excruciating Pain Caused by Trigeminal Neuralgia
Study Abstract Recognized as Best Clinical Abstract at 2022 Radiosurgical Society Meeting
TN occurs most frequently in people over the age of 50 years old and is more common in women than in men . A chronic pain condition affecting a craniofacial nerve that is primarily responsible for transmitting sensations from the face to the brain, TN is described by some patients as the most excruciating pain human beings can suffer. Pain can be brought on from the lightest of touches to the face, even a gently breeze can start a painful attack.
"Many people don't understand how debilitating the chronic pain associated with trigeminal neuralgia can be. If left untreated, or inadequately treated, it can be difficult to perform daily activities that most of us take for granted – from eating a meal, washing our face or brushing our teeth, to talking. That's why studies like this are so significant. They demonstrate that with treatment options like CyberKnife radiosurgery, we can provide our patients long-term pain control – without a rigid head frame, surgery or medications. We can offer our patients hope and the chance to once again focus on what's possible in their lives," said
TN can affect patients over the course of their lives, making long-term medical care a necessity. Treatment of TN usually begins with medication to block the pain signals sent to the brain. Over time, some medications become less effective, and certain patients experience unpleasant side effects. Alternative treatments, such as injections, radiofrequency, balloon compression, surgery or radiosurgery, may be required for these patients.
"Clinical data continues to confirm the durable benefits that CyberKnife radiosurgery can provide over the long term. The system delivers advanced radiotherapy treatments with sub-millimeter accuracy, which is of critical importance when treating tumors and lesions in the brain, while minimizing risk of potential side effects," said
The CyberKnife System was designed to treat diseases in the head and base of the skull, and functional disorders, with radiosurgery – without the use of a fixed frame bolted to the patient's head. The system features a linear accelerator (linac) directly mounted on a robot that moves and bends around the patient to deliver non-isocentric, non-coplanar radiation beams from potentially thousands of unique angles, facilitating highly precise and accurate treatments – typically in just one to five visits.
Using advanced imaging and
About the Study
The primary study objective was to evaluate the safety and effectiveness of CyberKnife radiosurgery in TN patients. A prescription dose of 60 Gy was delivered in a single fraction to a 6-mm segment of the nerve. The same dose was delivered if a second treatment was needed; over time the second dose was reduced to 45 Gy. All patients had taken medications for an average of 4.3 years before treatment with radiation.
Safe Harbor Statement
Statements made in this press release that are not statements of historical fact are forward-looking statements and are subject to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements in this press release relate, but are not limited, the CyberKnife platform's potential for the treatment of trigeminal neuralgia, the durable benefits of treatment with the CyberKnife platform, clinical applications, clinical results, patient experiences and outcomes, and
Forward-looking statements speak only as of the date the statements are made and are based on information available to the company at the time those statements are made and/or management's good faith belief as of that time with respect to future events. The company assumes no obligation to update forward-looking statements to reflect actual performance or results, changes in assumptions or changes in other factors affecting forward-looking information, except to the extent required by applicable securities laws. Accordingly, investors should not put undue reliance on any forward-looking statements.
Public Relations Director, Accuray
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 Romanelli P, Bianchi L, Beltramo G (
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