Accuray CyberKnife® Robotic Radiotherapy Platform Could Significantly Improve Survival in Early-Stage Breast Cancer Patients
Early-stage breast cancer treatment typically includes breast-conserving surgery followed by radiotherapy. The addition of radiotherapy can extend survival that may be offset by the development of a secondary cancer – like lung tumors – many years following treatment. Radiotherapy technology that has the ability to precisely deliver the prescribed radiation dose only to the target while minimizing dose to the surrounding healthy tissue is essential to reduce the incidence of secondary cancers.
"Important findings from this study of dynamic modeling using Real World Evidence (RWE) underscore the fact that we potentially can help to prevent unnecessary deaths related to radiation-induced secondary lung cancer associated with the treatment of early-stage breast cancer. Advanced radiotherapy techniques can decrease the dose to the lung delivered during breast cancer treatment with a probable reduction in risk of mortality," said
The CyberKnife platform, the first and only robotic radiotherapy platform, features a compact linear accelerator mounted on a highly maneuverable robotic arm that moves around the resting patient while delivering non-coplanar radiation beams from potentially thousands of unique angles, targeting only the tumor while minimizing radiation dose to healthy tissue. The CyberKnife platform is equipped with artificial intelligence (AI)-driven motion synchronization technology, Synchrony®, that adjusts the radiation beam to the patient or tumor movement, allowing the patient to breathe freely while keeping precisely on target throughout the treatment, automatically. Together, the CyberKnife robotic design with Synchrony facilitates the delivery of ultra-hypofractionated APBI with extreme accuracy and precision, reducing patient burden.
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About the Study
The purpose of the study was to determine the risk of developing radiation-induced secondary lung cancer (SLC) in patients diagnosed with early-stage breast cancer and whether different radiotherapy techniques could save lives. An analysis of the SEER database, the Surveillance, Epidemiology, and End Results Program, from 1988 to 2012 identified 765,697 non-metastatic breast cancers of which 49.8% received radiotherapy and were included in the study. The number of SLCs was calculated using the BEIR model, measuring the health risks from exposure to low levels of ionizing radiation, modified with data from the SEER database. Breast cancer stage distribution and number of new cases were obtained from the
About SEER
The SEER Program provides information on cancer statistics in an effort to reduce the cancer burden among the
About
Safe Harbor Statement
Statements made in this press release that are not statements of historical fact are forward-looking statements and are subject to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements in this press release relate, but are not limited, to the ability of the CyberKnife platform to improve survival in early-stage breast cancer patients, the CyberKnife platform's potential for the treatment of early-stage breast cancer, clinical applications, clinical results, patient experiences and outcomes, and
Forward-looking statements speak only as of the date the statements are made and are based on information available to the company at the time those statements are made and/or management's good faith belief as of that time with respect to future events. The company assumes no obligation to update forward-looking statements to reflect actual performance or results, changes in assumptions or changes in other factors affecting forward-looking information, except to the extent required by applicable securities laws. Accordingly, investors should not put undue reliance on any forward-looking statements.
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